Who are at risk of a BRCA mutation?A family history of cancer can suggest increased risk. For women, these patterns include:
- Having a male relative with breast cancer.
- Having a mother, daughter, or sister with bilateral breast cancer.
- Having 2 first-degree relatives: mother, daughter, or sister who had breast cancer at or before age 50.
- Having at least 3 first- or second-degree relatives, including grandmothers and aunts, diagnosed with breast cancer at any age, or at least 2 relatives with ovarian cancer.
- Having first- and second-degree relatives with breast or ovarian cancer, particularly if a relative has had both breast and ovarian cancer, regardless of the age at diagnosis.